Brown lab graduate students are listed in bold and undergraduate contributors are underlined.
Submitted or In Revision
M. Howell, A. Aliashkevich, K. Sundararajan, J.J. Daniel, P.J. Lariviere, E.D. Goley, F. Cava, and P.J.B. Brown. Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division. Submitted.
C. Zhang, P.J.B. Brown, and Z. Hu. Higher functionality of plasmid DNA after inactivation of bacteria by peracetic acid compared to free chlorine. Submitted.
C. Zhang, P.J.B. Brown, R.J. Miles, T.A. White, D. Grant, D. Stalla, and Z. Hu. Regrowth of planktonic and biofilm bacteria after disinfection with peracetic acid. Submitted.
M.A. Williams, D.T. Kysela, and P.J.B. Brown. 2018. Diversity of Growth Patterns in the Alphaproteobacteria. Cell Cycle Regulation and Development in Alphaproteobacteria. Emanuale Biondi, editor. Submitted.
H. Attai, M. Boon, K. Phillips, J.P. Noben, R. Lavigne, and P.J.B. Brown. 2018. Larger than life: Isolation and genomic characterization of a jumbo phage that infects the bacterial plant pathogen, Agrobacterium tumefaciens. Front Microbiol 9, 1861.
L. Liao, A.L. Schaefer, B.G. Coutinho, P.J.B. Brown, and E.P. Greenberg. 2018 A novel aryl-homoserine lactone quorum-sensing signal produced by a dimorphic prosthecate bacterium. Proc Natl Acad Sci. doi:10.1073/pnas.1808351115.
W. Figueroa-Cuilan and P.J.B. Brown. 2018. Cell growth and division in the plant pathogen A. tumefaciens. Current Topics in Microbiology and Immunology volume on Agrobacterium Biology. Stanton Gelvin, editor. Accepted.
C. Zhang, D. Parrello, P.J.B. Brown, J.D Wall, and Z. Hu. A whole-cell biosensor of Pseudomonas aeruginosa to monitor expression of quorum-sensing genes. Appl Microbiol Biotechnol. 102:6023-6038.
S.A. Flores*, M. Howell*, J. J. Daniel, R. Piccolo, and P.J.B. Brown. Absence of the Min system does not cause major cell division defects in Agrobacterium tumefaciens. Front Microbiol 9, 681.
C. Zhang, P.J. Brown, and Z. Hu. 2018. Thermodynamic properties of peracetic acid as an emerging chemical disinfectant. STOTEN. 621:948-959.
M.A. Williams, P. Friedrichsen, T. Sadler, and P.J.B. Brown. Modeling the emergence of antibiotic resistance in bacterial populations. Am Biol Teach. 80:214-220.
H. Attai, J. Rimbey, G.P. Smith, and P.J.B. Brown. 2017. Expression of a peptidoglycan hydrolase from lytic bacteriophages Atu_ph02 and Atu_ph03 triggers lysis of Agrobacterium tumefaciens. Appl Environ Microbiol. 83:e01498-17.
M. Howell, J.J. Daniel, and Pamela J.B. Brown. 2017. Live cell fluorescence microscopy to observe essential processes during microbial cell growth. J Vis Exp. 129:e56497.
M. Howell, A. Aliashkevich, A.K. Salisbury F. Cava, G.R. Bowman, and Pamela J.B. Brown. 2017. Absence of the polar organizing protein PopZ results in reduced and asymmetric cell division in Agrobacterium tumefaciens. J Bacteriol. 199:e00101-17.
M. Howell and P.J.B. Brown. 2016. Building the bacterial cell wall at the pole. Curr Opin Microbiol 34:53-59.
Figueroa-Cuilan*, J.J. Daniel*, M. Howell, A. Sulaiman, and P.J.B. Brown. 2016. Mini-Tn7 insertion in an artificial attTn7 site enables depletion of the essential master regulator CtrA in the phytopathogen Agrobacterium tumefaciens. Appl Environ Microbiol 82:5015-5025.
M.A. Williams*, M.D. Hoffman*, J.J. Daniel, S.M. Madren, A. Dhroso, D. Korkin, S.C. Jacobson, and P.J.B. Brown. 2016. Short-stalked Prosthecomicrobium hirschii cells have a Caulobacter-like cell cycle. J Bacteriol. 198: 1149-1159.
P.J. Friedrichsen, T.D. Sadler, K. Graham, and P. Brown. 2016. Design of a socio-scientific issue curriculum unit: Antibiotic resistance, natural selection and modeling. International Journal of Designs for Learning. 7:1-18.
J.J. Daniel, S.A. Givan, Y.V. Brun, and P.J.B. Brown. 2015. Draft genome sequence of Prosthecomicrobium hirschii ATCC 27832T. GenomeA. 3:e01355-15.
M.D. Hoffman, L.I. Zucker, P.J.B. Brown, D.T. Kysela, Y.V. Brun, and S.C. Jacobson. 2015. Timescales and frequencies of reversible and irreversible adhesion events of single bacterial cells. Anal Chem. 87:12032-12039
C. Jiang, P.J.B. Brown, A. Ducret, and Y.V. Brun. 2014. Co-option of a developmental regulator in the sequential evolution of bacterial morphology. Nature. doi:10.1038/nature12900
D.T. Kysela*, P.J.B. Brown*, K.C. Huang, Y.V. Brun. 2013. Biological Consequences and Advantages of Asymmetric Bacterial Growth. Annu Rev Microbiol. 67:417-435. *equal contributions.
A. Sims, Y. Zhang, S. Gajaraj, P.B. Brown, and Z. Hu. 2013. Towards the development of microbial indicators for wetland assessment. Water Res. 47:1711-1725.
Z. Wan, P.J.B. Brown, E.N. Elliott, and Y.V Brun. 2013. The adhesive and cohesive properties of a bacterial polysaccharide adhesion are modulated by a deacetylase. Mol Microbiol. 88:486-500.
E. Kuru, H.V. Hughes, P.J. Brown, E. Hall, S. Tekkam, F. Cava, M.A. de Pedro, Y.V. Brun, and M.S VanNieuwenhze. 2012. In situ probing of newly synthesized peptidoglycan in live bacteria with fluorescent D-amino acids. Angew Chem. 51:12519-12523. Cover article. Selected by journal as “hot paper”. Nature Reviews Microbiology Research Highlight: 2012. Techniques & applications: Shedding light on peptidoglycan growth. Nature Rev Microbiol. 10:802. Featured in NIH Biomedical Beat, Chemical and Engineering News, The American Scientist, Nature Chemistry, and NPR, A Moment of Science.
S.M. Madren, M.D. Hoffman, P.J.B. Brown, David T. Kysela, Yves V. Brun, and Stephen C. Jacobson. 2012. Microfluidic device for automated synchronization of bacterial cells. Anal Chem. 84:8571-8578. Featured in Chemical and Engineering News.
V.R Pejaver, A. Bhan, J-H. Choi, B. Liu, H. Lee, P.J Brown, D. Kysela, Y.V. Brun and S. Kim. 2012 GeneclusterViz: a tool for conserved gene cluster visualization, exploration and analysis. Bioinformatics. 28:1527-1529.
P.J.B. Brown, M.A. de Pedro, D.T. Kysela, C.V.d. Henst, X. DeBolle, C. Fuqua, and Y.V. Brun. 2012. Polar growth in the Alphaproteobacterial Order Rhizobiales. Proc Natl Acad Sci. 109:1697-1701. Science Editor’s Choice Highlight: 2012. Live to divide another way. Science. 335:775. Recommended by Faculty of 1000.
G. Li*, P.J.B. Brown*, J.X. Tang, J. Xu, E.M. Quardokus, C. Fuqua and Y.V. Brun. 2012. Stimulation of bacterial adhesin production by surface contact. Mol Micro. 83:41-51.*equal contributions. Cover feature and cover image. Accompanied by a commentary article. Recommended by Faculty of 1000. Highlighted in NIH Biomedical Beat and NSF Research in Action series.
Chertkov, O., P.J.B. Brown, D.T. Kysela, 18 authors, H.-P. Klenk, Y.V. Brun. 2011. Complete genome sequence of Hirschia baltica type strain (IFAM 1418T). 2011. Stand Genomic Sci. 5:287-297.
P.J.B. Brown*, D.T. Kysela*, and Y.V. Brun. 2011. Polarity and the diversity of growth mechanisms in bacteria. Semin Cell Dev Biol. 22: 790-798. *equal contributions
P.J.B. Brown, D.T. Kysela, A. Buechlein, C. Hemmerich, and Y.V. Brun. 2011. Genome sequences of eight morphologically diverse Alphaproteobacteria. J. Bacteriol. 193:4567-4568.
M.L. Kovarik, P.J.B. Brown, D.T. Kysela, C. Berne, A.C. Kinsella, Y.V. Brun, and S.C. Jacobson. 2010. Microchannel-Nanopore Device for Bacterial Chemotaxis Assays. Anal. Chem. 82:9357–9364.
G.G. Hardy, R.C. Allen, E. Toh, M. Long, P.J.B. Brown, J.L. Cole-Tobian, Y.V. Brun. 2010. A localized multimeric anchor attaches the Caulobacter holdfast to the cell pole. Mol Microbiol. 76:409-427.
P.J.B. Brown, G.G. Hardy, M.J. Trimble, and Y.V. Brun. 2009. Complex regulatory pathways coordinate cell cycle progression and development in Caulobacter crescentus. Adv Micro Phys. 54:1-101.
P.J. Bonner and L.J. Shimkets. 2006. Phospholipid directed motility of surface-motile bacteria. Mol Microbiol. 61:1101-1109.
P.J. Bonner, W.P. Black, Z. Yang, and L.J. Shimkets. 2006. FibA and PilA act cooperatively during fruiting body formation of Myxococcus xanthus. Mol Microbiol. 61:1283-1293.
P.J. Bonner and L.J. Shimkets. 2006. Cohesion defective mutants of Myxococcus xanthus. J. Bacteriol. 188:4585-4588.
P.J. Bonner, Q. Xu, W.P Black, Z. Li, Z. Yang, and L.J Shimkets. 2005. The dif chemosensory pathway is directly involved in phosphatidylethanolamine sensory transduction in Myxococcus xanthus. Mol Microbiol. 57:1499-1508.
Kearns, D.B., P.J. Bonner, D.R. Smith, and L.J. Shimkets. 2002. An extracellular zinc metalloprotease is required for dilauroyl phosphatidylethanolamine chemotactic excitation in Myxococcus xanthus. J. Bacteriol. 184:1678-1684.
Kearns, D.B., A. Venot, P.J. Bonner, B. Stevens, G-J. Boons, and L.J. Shimkets. 2001. Identification of a developmental chemoattractant in Myxococcus xanthus through metabolic engineering. Proc. Natl. Acad. Sci. USA 98:13990-13994.
P.J. Bonner and L.J. Shimkets. 2001. Piecing together a puzzling pathway: new insights into C-signaling. Trends Microbiol. 9:462-464.